The short answer
The official starting advice favours a small set of offensive weapons and concentrating upgrades instead of spreading choices too thin. Use that as a simple learning goal: understand how a few choices affect a run before trying to optimise everything.
Make one thing the purpose of a run
Choose a learning question before you start, such as whether a particular upgrade helps you manage a difficult moment. This is an editorial exercise, not a tested winning build. Changing every choice at once makes it harder to tell what helped.
Treat a failed run as information
After a run, write down one decision you would change and one decision you would repeat. That keeps the next attempt specific. Avoid copying an old build as though it must match the current game version, your available unlocks and your preferences.
Check inputs before choosing a device
The Steam description lists several input methods. That is a compatibility starting point, not a performance result. Check current device requirements and input settings before purchasing or planning a shared session; we have not measured frame rates or battery life.
Where to go next
Return to the game page for recorded price and the official store link. Use the Play together guide if local cooperative play is the reason you are interested. For exact unlock conditions, consult the current in-game information rather than inferring them from a general first-run guide.